1. Sex is fixed from the first cell onward
Every person’s body is built along one of two reproductive pathways: the pathway that can make sperm (male) or the pathway that can make eggs (female). This plan is written into every cell and cannot be rewritten later. One detrans man, after years on hormones and surgery, put it bluntly: “People can’t change sex. We are mammals, not slugs. No matter what hormones you take or what surgeries you have, you can’t change the biological pathway that your body developed along.” – Ok_Bullfrog_8491 source [citation:1766af41-2feb-4008-92ef-e9007e0bdc50]
In other words, removing or altering body parts does not switch the underlying blueprint; it only changes appearance.

2. Medical transition does not create the other sex; it removes healthy function
Surgeries and cross-sex hormones can reshape the body’s outward look and stop natural hormone production, but they do not give anyone the gonads, chromosomes, or lifelong endocrine rhythms of the other sex. A detrans woman explained her realization: “Breaking down a car doesn’t make it no longer a car… Losing the function of producing these gametes doesn’t change sex either, because it’s defined by your original developmental pathway.” – ExternalPersonal6059 source [citation:cfeb1a67-1136-4288-b5b8-71597d77e964]
Many who detransition describe grief at discovering that the procedures they hoped would make them the other sex had instead left them sterile and still biologically the same sex.

3. The animal “sex-change” comparison is biologically misleading
Clownfish, slugs, and a few other species can naturally reorganize their reproductive systems; humans cannot. A detrans woman clarified: “Some animals can fly, breathe underwater, regenerate limbs… humans can’t do any of those things either. It simply isn’t in our biology.” – DraftCurrent4706 source [citation:c0d4c3f4-67e2-455e-8a90-f1fcc90db73d]
Using these rare animal abilities to justify human medical transition sets people up for disappointment when the promised transformation never materializes.

4. Intersex conditions do not prove that sex is changeable
A small percentage of people are born with atypical genitalia or chromosomal patterns, yet even they have an underlying sex pathway. One intersex man—born with ambiguous genitalia, surgically shaped male in infancy, and XX chromosomes—still needs lifelong testosterone to approximate typical male levels. He reports: “I have XX chromosomes, and if I wasn’t supplementing my T I’d be about halfway between the normal average expected levels for male and female.” – mrsc0tty source [citation:5ccf9d7c-5971-4931-84f3-b9a4fb70eb9d]
His story shows that medical intervention can support a body’s existing pathway but cannot flip it to the other sex.

5. Freedom comes from embracing the body you have
Many who stepped away from transition found peace by rejecting the idea that they had to “become” the other sex to feel whole. They discovered that discomfort with gender roles is best solved by expanding those roles, not by altering the body. As one detrans man concluded, “It’s only when you do the aftermath that you realize how sex change is such a foolish contradiction of reality.” – Stuckinmiddleground source [citation:262d64da-e20f-4d55-9750-f0602a4e58bd]
Understanding that sex is unchangeable can feel daunting at first, but it also opens the door to self-acceptance, creative gender non-conformity, and mental-health support that affirms the whole person without medical risk.